![]() Chemicals used to produce fentanyl can cost $75 or more per kilogram. Chinese websites sell a kilogram for $6 to $20, no prescription required. Like other cutting agents, xylazine benefits dealers: It’s often cheaper and easier to get than fentanyl. Some users say the combination, dubbed “tranq” or “tranq dope,” gives a longer-lasting high, more like heroin, which has largely been replaced by fentanyl in U.S. In almost all cases, xylazine - a drug for sedating horses and other animals - is added to fentanyl, the potent opioid that can be lethal even in small amounts. response to the opioid crisis, causing gruesome skin wounds and scrambling longstanding methods for treating addiction and reversing overdoses. Xylazine, a powerful animal sedative that's moving through the illicit drug supply is complicating the U.S. “Then I wake up, trying to piece together what happened.” Matt Rourke/AP Show More Show Less 14 of21 Dominic Rodriguez speaks with registered nurse Kathy Lalli after she treated his skin injuries at the Kensington Hospital wound care outreach van, parked in the Kensington neighborhood of Philadelphia, Tuesday, May 23, 2023. “It’s a delayed reaction, I could be walking down the street, it's 45 minutes later,” says Rodriguez, who is homeless and battling addiction. Xylazine’s effects are easy to spot: users experience a lethargic, trance-like state and sometimes black out, exposing themselves to robbery or assault. Matt Rourke/AP Show More Show Lessġ2 of21 13 of21 Dominic Rodriguez speaks with registered nurse Kathy Lalli after she treated his skin injuries at the Kensington Hospital wound care outreach van, parked in the Kensington neighborhood of Philadelphia, Tuesday, May 23, 2023. ![]() Experts disagree on the exact cause of the wounds, which are much deeper than those seen with other injectable drugs. It’s also linked to severe skin ulcers and abscesses, which can lead to infections, rotting tissue and amputations. In humans, xylazine can cause breathing and heart rates to drop. Matt Rourke/AP Show More Show Less 5 of21 Registered nurse Kathy Lalli treats Ellwood Warren's injuries at the Kensington Hospital wound care outreach van, parked in the Kensington neighborhood of Philadelphia, Tuesday, May 23, 2023. Xylazine can cause severe skin wounds, but whether it is leading to more deaths - as suggested by officials in Washington - is not yet clear, according to health and law enforcement professionals on the front lines of efforts in New Jersey, New York and Pennsylvania. ![]() ![]() 3 of21 4 of21 Nick Gallagher reacts as volunteer registered nurse Jennifer D'Angelo treats his skin wounds the Savage Sisters' community outreach storefront in the Kensington neighborhood of Philadelphia, Wednesday, May 24, 2023. ![]()
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